Home  |  Journals  |  Conferences |   Membership  |   FAQ's Join  |  Contact  |   Sitemap  |             

International Journal of Clinical & Medical Images

ISSN: 2376-0249
Open Access
 
 
 

A Case of Cold Agglutinin Disease Associated with Mycoplasma Pneumonia

Other Art Works

Image 01 Image 02
Image 03 Image 04
Image 05 Image 06
Image 07 Image 08
Image 09 Image 10
Image 11 Image 12
Image 13 Image 14
Image 15 Image 16
Image 17 Image 18
Image 19 Image 20
Image 21 Image 22
Image 23 Image 24
Image 25 Image 26
Image 27 Image 28
Image 29 Image 30

A 19-year-old male patient was admitted to the hospital with a fever and cough. His chest X-ray showed right lower lobe infiltration consistent with the diagnosis of pneumonia. On the fifth day after admission, he started complaining about dark urine and jaundice, and his hemoglobin level dropped from 14 g/dl to 8 g/dl, with up regulation of unconjugated bilirubin. The nurses noticed clotting of his blood immediately after they drew the blood. A blood smear without magnification on the left side in Figure 1 (panel A) is the control; the patient’s blood smear (panel B) showed clumps before staining. Warming to 37°C at room temperature caused his blood to undergo agglutination (Figure 2, arrow). Results of a cold-agglutinin test were strongly positive (anti-I). Serological testing for mycoplasma showed a high titer of anti-mycoplasma IgM (without IgG). The patient was treated with levofloxacin and showed an excellent response; his cold agglutinin disease resolved. As seen in the current patient, potent cold agglutinins can cause specific problems, especially when reactivity persists at temperatures above room temperature. The acute form of cold agglutinin disease is often secondary to mycoplasma infection or lymphoproliferative disorders

 
 
© 2008-2013 OMICS Group - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version