International Journal of Clinical & Medical Imaging | OMICS International | Editorial Board
Home  |  Journals  |  Conferences |   Membership  |   FAQ's
Join  |  Contact  |   Sitemap  |                
OMICS Group Inc

International Journal of Clinical & Medical Images

ISSN: 2376-0249 Open Access

Squamous Cell Carcinoma in an Albino

Other Art Works

Image 01 Image 02
Image 03 Image 04
Image 05 Image 06
Image 07 Image 08
Image 09 Image 10
Image 11 Image 12
Image 13 Image 14
Image 15 Image 16
Image 17 Image 18
Image 19 Image 20
Image 21 Image 22
Image 23 Image 24
Image 25 Image 26
Image 27 Image 28
Image 29 Image 30

A 30-year old albino woman was referred by a dermatologist for excision of a large ulcerated and fungating squamous cell carcinoma (6 x 5cm) on the outer aspect of the right arm. (Figure 1) There was neither palpable axillary lymphadenopathy nor evidence of distant metastases and, she was otherwise clinically well. Successful removal necessitated the excision of a sufficiently wide margin of surrounding tissue (1cm) with the primary growth. The tumour was seen to invade the deep fascia of the underlying muscle and careful fasciectomy with sparing of the musculocutaneous nerve was performed. (Figure 2) The resulting large defect in the tight compartment of the arm made closure difficult. Skin grafting was not done in the uncertainty of adequate clearance of the malignant lesion and certainly not directly over muscle. However, to facilitate healing, careful undermining of the adjacent tissues permitted partial closure of the defect. (Figure 3) The wound healed successfully within 4 weeks and there was no evidence of local recurrence 5 months later. Albinism is an inherited autosomal recessive disorder characterized by lack of skin pigmentation. It appears to be the most important risk factor in the development of squamous cell carcinoma through the malignant transformation of active keratosis 9 [1,2]. It is also the commonest cause of death in young African albinos [2]. Treatment entails locoregional control by surgical excision along with block dissection of involved regional glands [3]. Radiotherapy alone may provide palliation when gland dissection is impracticable.