International Journal of Clinical & Medical Images

Clinical Image

Non-Hodgkin lymphomas are neoplasms of the lymphatic system originating from the lymphoid cells of the B, T and NK cell lines. The most common subtype is DLBCL. Secondary skin involvement may appear in almost 25% of all non-Hodgkin’s lymphomas and the lesions cloud presented as papules, nodules, plaques, ulcers or a combination of these. A 69-year-old man presented on June of 2018 with B symptoms, cervical adenopathies and was a diagnostic with diffuse large B cell lymphoma (DLBC). He was treated with half dose of chemotherapy, due to cardiopathy and stay on maintenance with rituximab in the following 18 months. On January 2020, at the schedule appointment the patient exhibited multiple painless, indurated, violaceus lesions on both low extremities (Figure 1) and another lesion on the right arm (Figure 2), with 2 months of evolution. The biopsy of the skin lesion and cytometry confirms the relapse of DLBC. He started on palliative chemotherapy due to cardiopathy.