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International Journal of Clinical & Medical Images

2376-0249

Clinical Image - International Journal of Clinical & Medical Images (2024) Volume 11, Issue 5

Comparison of Octreotide Scintigraphy and Conventional Imaging in Detection of Metastatic Medullary Thyroid Carcinoma Case Report

Comparison of Octreotide Scintigraphy and Conventional Imaging in Detection of Metastatic Medullary Thyroid Carcinoma Case Report

Author(s): Amellouk Sara*, Bennani Hakim, Bensmimou Hafsa, Batani Halima, Oussafrar Zakaria and Guensi Amal

Medullary Thyroid Carcinoma (MTC) is a rare neuroendocrine tumor arising from the parafollicular C cells of thyroid. It represents
approximately 5% of all thyroid carcinomas. MTC is frequently aggressive and metastatic sites are generally cervical and mediastinal lymph
nodes, lungs, liver, and bones. The initial treatment consists of a total thyroidectomy with bilateral neck lymph node and upper mediastinum dissection [1]. Somatostatin receptors are often over-expressed in Medullary Thyroid Carcinoma (MTC), the aim of our study was to evaluate
the utility of scintigraphy with the somatostatin analogue 99mTc- Tektrotyd in metastatic MTC in comparison with other conventional imaging
techniques. Nuclear imaging modalities are sensitive in detecting small amounts of residual or recurrent tumor at an early stage that may not
be visible on conventional imaging, helping to guide treatment decisions and improve patient outcomes [2]. Normalization of serum calcitonin
levels after surgery is a strong indicator that neoplastic tissue was totally removed.

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Citations : 293

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