International Journal of Clinical & Medical Images

The human acellular dermal matrix is widely utilized in medical applications due to its structural and functional properties, providing a scaffold for tissue repair and regeneration. However, its clinical performance often depends on its biocompatibility and biointegration. Enhancing these properties is essential to improving the efficacy of HADM in diverse applications. Vacuum plasma surface treatment has emerged as a promising technique to modify biomaterials and optimize their interactions with host tissues. Vacuum plasma treatment involves the generation of ionized gas under controlled conditions to alter the surface characteristics of materials. When applied to HADM, this technique enhances its surface energy and introduces functional groups that promote cell adhesion, proliferation, and differentiation. These modifications create a more favorable environment for cellular integration, leading to improved tissue regeneration and healing outcomes.