International Journal of Clinical & Medical Images

Clinical Image

An 83-year-old man presented with a voluminous exophytic lesion on forehead that had been quickly increasing in size during the past 3 months. The lesion had become progressively corneous, with intermittent bleeding. 

The physical examination revealed a well-defined frontal horn measuring 5 × 3 cm in diameter (Figures 1-3). A Cutaneous Squamous Cell Carcinoma (CSCC) was identified on biopsy. Unfortunately the patient had a heart attack and he was hospitalized in a cardiac care unit for a month. When the general conditions allowed a general anaesthesia the patient underwent a surgical debulking of the lesion but he died before starting oncological therapy from complications of cardiovascular disease. CSCC arises from the malignant proliferation of epidermal keratinocytes. It is the second most common cause of death from skin cancer after melanoma; its incidence continues to rise and is an underestimate [1-3].

Keywords: Frontal Horn; Carcinoma

Declaration of Interests

The authors declare that they have no competing interests.

References

1. Alam M, Ratner D (2001) Cutaneous squamous-cell carcinoma. NEJM 344:975-983.
2. Rogers HW, Weinstock MA, Feldman SR, Coldiron BM (2015) Incidence estimate of non-melanoma skin cancer (keratinocyte carcinomas) in the US population 2012. JAMA Derm 151:1081-1086
3. Brougham ND, Tan ST (2014) The incidence and risk factors of metastasis for cutaneous squamous cell carcinoma-implications on the T-classification system. J Surg Oncol 110: 876-882